| Date | Home | Away | Result |
|---|---|---|---|
| 23/09/25 16:00 | Cagliari Calcio | Frosinone Calcio | --- |
| 23/09/25 17:30 | Udinese Calcio | Palermo FC | --- |
| 23/09/25 20:00 | AC Milan | US Lecce | --- |
| 24/09/25 16:00 | Parma Calcio 1913 | Spezia Calcio | --- |
| 24/09/25 17:30 | Hellas Verona | FC Venice | --- |
| 24/09/25 20:00 | Como Calcio | Sassuolo Calcio | --- |
| 25/09/25 17:30 | Genua CFC | FC Empoli | --- |
| 25/09/25 20:00 | FC Turin | Pisa Sporting Club | --- |